The Role of Functional MRI in The Evaluation of The Treated Head and Neck Squamous Cell Carcinoma

Background: The diffusion-weighted imaging (DWI) with apparent diffusion coefficient (ADC) map and the dynamic contrast-enhanced magnetic resonance (DCE-MRI) constitute functional MRI technique many oncological applications as it can define tissue microstructure characterize post-treatment changes from a recurrent tumor in treated head neck squamous cell carcinoma (HNSCC). Objective: To evaluate role of DWI, ADC DCE-MRI for characterization tumors patients HNSCC. Patients Methods: Forty-five HNSCC were included this study mean ages 59 ± 7.5 years. underwent pre post-contrast MRI, DWI DCE-MRI, each diagnosis was then compared to patient outcome. Results: sensitivity specificity qualitative (DW-MRI) (87.5% 82.8% respectively) higher than conventional (75% 75.9% respectively). cut-off point recurrence 1.095 x10-3 mm2/s 87.5%, 86.2% respectively. DCE- revealed significant difference type time intensity curve (TIC) between lesion (p-value < 0.0001). Conclusion: be used synchronized tool differentiation patients.